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How long is Antabuse effective? The half life of Antabuse is 60-120 hours and up to 20% of a single dose may remain in the body for a week or more. Antabuse starts to affect ethanol metabolism within 1-2 hours after administration. Following a single dose of the medication, the body may react to any amount of alcohol for up to 14 days.
Can you take naltrexone and Antabuse together? Naltrexone and disulfiram are medications currently approved for treating alcohol dependence. These two medications have different mechanisms of action in the body. In combination they might be effective in treating individuals dually diagnosed with cocaine and alcohol dependence.
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